Canine Parvovirus Antigen Quantitative Kit (Fluorescent Immunochromatography Assay of Rare Earth Nanocrystals)(CPV Ag)

[Product Name]

CPV one step test


[Packaging Specifications]

10 tests/box

Product Detail

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Purpose of Detection

Canine parvovirus is a parvovirus Genus parvovirus of the family Viridae, can cause intense infectious diseases in dogs. one Generally there are two clinical manifestations: hemorrhagic enteritis type and myocarditis type, two All patients have high mortality, high infectivity and short course of disease, especially Higher rates of infection and mortality in puppies. So reliable, have The detection of efficacy plays a positive guiding role in prevention, diagnosis and treatment.


Detection result

Normal range: < 8 IU/ml
Carry: 8~100 IU/ml (there is a risk of disease, please continue to observe and test)
Positive: > 100 IU/ml


Detection Principle

This product uses fluorescence immunochromatography for the quantitative detection of CPV in dog feces The content. Basic principle: There are T, C and T lines on the nitrate fiber membrane respectively Coated with an antibody a that specifically recognizes the CPV antigen. The combination pad is sprayed with energy CPV is specifically recognized by another fluorescent nanomaterial labeled antibody b, like The CPV in this paper first binds to the nanomaterial labeled antibody b to form a complex, The complex then binds to the T-line antibody a to form a sandwich Structure, when the excitation light irradiation, nanomaterials emit fluorescence signal, while the The strength of the signal was positively correlated with the CPV concentration in the sample.


Clinical Signs And Symptoms

Clinical symptoms can be roughly divided into: enteritis type, myocarditis type, systemic infection type and inconspicuous infection type four types.
(1)enteritis type The symptoms of enteritis caused by canine parvovirus infection are well known, and the virulence required for infection is quite low, about 100 TCID50 virus is sufficient. The prodromal symptoms are lethargy and anorexia, followed by acute dysentery (hemorrhagic or non-hemorrhagic), vomiting, dehydration, rising body temperature, weakness, etc. The severity of the symptoms depends on the age of the dog, the state of health, the amount of virus ingested, and other pathogens in the intestine. General enteritis symptoms, the course of the disease is: the initial 48 hours, loss of appetite, sleepiness, fever (39.5℃ ~ 41.5℃), then began to vomit, before vomiting within 6 to 24 hours, accompanied by the following diarrhea, the initial yellow, gray and white, and then mucous or even smelly blood diarrhea. The dog was severely dehydrated due to constant vomiting and dysentery. On clinicopathological examination, in addition to obvious dehydration, a significant reduction in white blood cells as low as 400 to 3,000/l is the most commonly detected lesion result. ​
(2)myocarditis type This type is only found in young sick dogs from 3 to 12 weeks of age, most of which are under 8 weeks of age. The mortality rate is very high (up to 100%), and irregular breathing and heartbeat can be seen clinically. In acute cases, it can be seen that the apparently healthy puppy suddenly collapses and has difficulty breathing, and then dies within 30 minutes. Most cases died within 2 days. Subacutely infected, puppies can also die within 6 months due to cardiac dysplasia. Since most female dogs already have antibodies to the disease (from vaccination or natural infection), the mother to the puppies can protect the puppies from the infection of the disease, so myocarditis type is quite rare. ​
(3)Systemic infection It has been reported that puppies within 2 weeks of birth died from infection with the disease, and the autopsy lesions showed extensive hemorrhagic necrosis of many major organs in the body. ​
(4) inconspicuous infection type That is, after infection, the virus can proliferate in dogs and then be excreted in the feces. But the dogs themselves showed no clinical symptoms. This type of infection is most common in dogs older than one year of age, or dogs that have been injected with the inactivated virus vaccine.

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