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Canine Parvovirus/Canine Coronavirus Antigen Test Kit (CPV Ag/CCV Ag)
Detection Purpose
Canine Parvovirus (CPV) belongs to the Parvovirus genus of the Parvoviridae family and can cause a highly contagious disease in dogs. There are generally two clinical manifestations: hemorrhagic enteritis type and myocarditis type, both of which are characterized by high mortality, strong infectivity, and rapid disease progression, especially in puppies, which exhibit higher infection rates and mortality.
Canine Coronavirus (CCV) belongs to the Coronavirus genus of the Coronaviridae family and is a highly hazardous infectious disease in dogs. Common clinical symptoms include gastroenteritis, specifically vomiting, diarrhea, and anorexia.
Due to the risk of mixed infections of CPV and CCV, reliable and effective detection methods play a crucial role in guiding prevention, diagnosis, and treatment.
Detection Principle
This product employs fluorescent immunochromatography to quantitatively detect the levels of CPV and CCV in canine feces. The basic principle is as follows: Nitrocellulose membranes are marked with T and C lines, where the T1 and T2 lines are coated with antibodies a and b, respectively, which specifically recognize CPV and CCV antigens. The conjugate pad is sprayed with another fluorescent nanomaterial-labeled antibody (c and d) that specifically recognizes CPV and CCV. The CPV and CCV in the sample first bind to the nanomaterial-labeled antibodies c and d to form a complex, which then migrates upward through chromatography. The complex binds to antibodies a and b on the T1 and T2 lines, forming a sandwich structure. When exposed to excitation light, the nanomaterial emits a fluorescent signal, and the intensity of this signal is positively correlated with the concentration of CPV and CCV in the sample.
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