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Canine C-Reactive Protein Test Kit（cCRP）
Testing Purpose
Canine C-Reactive Protein (cCRP) is an acute-phase reactive protein in dogs. It can be used as a sensitive indicator of canine systemic inflammation. During inflammation, the concentration level of cCRP in blood increases obviously and rapidly. As the inflammation subsides, the concentration level will quickly drop to normal. Although cCRP is a non-specific reactive protein, it has a good guiding role in detecting microbial infections, assessing the condition and severity of diseases, and monitoring the effects and process of treatment, especially for the rational use of antibiotics.
Detection Principle
This product utilizes fluorescence immunochromatography to quantitatively detect the cCRP content in whole blood, serum or plasma. The basic principle is as follows: T and C lines are respectively marked on the nitrocellulose membrane. The T line is coated with an antibody a that specifically recognizes the cCRP antigen. The binding pad is sprayed with another fluorescent nanomaterial-labeled antibody b that specifically recognizes cCRP. The cCRP in the sample first combines with the nanomaterial-labeled antibody b to form a complex. Then, through chromatography, the complex moves upward. The complex binds to the T-line antibody a, forming a sandwich structure. When the test strip is irradiated by excitation light, the nanomaterial emits a fluorescent signal, and the intensity of this signal is positively correlated with the concentration of cCRP in the sample.
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