Feline Health Markers 5-in-1 Combo Test Kit (fPL/CG/fCysC/fNT-proBNP/fTIgE)

Feline Pancrelipase (fPL) is an indicator related to the inflammatory infiltration disease of the pancreas in cats. Pancreatitis in cats is generally divided into acute pancreatitis and chronic pancreatitis. Acute pancreatitis is characterized by neutrophil infiltration, pancreatic necrosis, fat necrosis around the pancreas, edema, and tissue injury. Chronic pancreatitis is manifested as pancreatic fibrosis and atrophy. Compared with acute pancreatitis, chronic pancreatitis is less harmful but occurs more frequently. When a cat has pancreatitis, the pancreas is damaged, and the levels of pancreatic lipase in the blood increase rapidly. Currently, pancreatic lipase is one of the best specific indicators for the diagnosing of feline pancreatitis.

Cholyglycine (CG) is one of the conjugated bile acids formed by combining bile acid with glycine. It is the main bile acid component in serum during late pregnancy. When hepatocytes are damaged, their ability to break down CG decreases, resulting in an increased CG level in the blood. When bile stagnation occurs, the liver cannot excrete bile acid, and the amount of CG returning to the circulation increases, thus also raising the blood CG level. 

Cystatin C is one of cysteine protease inhibitor proteins. CysC is an endogenous substance that, so far, basically meets the requirements of ideal endogenous GFR(glomerular filtration rate) markers. It is a newly-developed indicator featuring good sensitivity and high specificity for evaluating cat kidney function.

Feline N-terminal pro-brain natriuretic peptide (fNT-proBNP)is a substance secreted by cardiomyocytes in the feline ventricle. It can be used as a detection indicator for corresponding heart failure. The concentration of fNT-proBNP in the blood is related to the severity of the disease. Consequently, fNT-proBNP cannot only assess the severity of acute and chronic heart failure but also serve as an indicator of the prognosis of the disease.

Feline Total IgE is a class of immunoglobulin (Ig) with a molecular weight of 188kD. It exists at a relatively low level in serum. It is commonly used in the diagnosis of allergic reactions and can also assist in diagnosing parasitic infections and multiple myeloma.

1. Allergic Reactions: When an allergic reaction occurs, it causes the level of allergen lgE to raise. The higher the level of allergen lgE is, the more severe the allergic reaction will be.

2. Parasitic Infections: When a pet is infected by parasites, the level of allergen lgE may also increase. This is generally associated with the mild allergy induced by the protein of the parasites. Additionally, reports indicate that tumors may also cause the elevation of total IgE.