Feline parvovirus (FPV) can cause severe infectious diseases in cats. The general clinical manifestations include high fever, diarrhea, vomiting and other symptoms. It is characterized by high mortality, high infectivity and a short course of disease, especially for young cats, which have a higher infection rate and mortality. Detecting FPV antibody levels in cats can reflect the body's immune status.
Feline calicivirus (FCV) infection is a viral respiratory-tract infectious disease in cats. The general clinical manifestations mainly involve upper respiratory-tract symptoms, such as mental depression, serous and mucinous rhinorrhea, conjunctivitis, stomatitis, tracheitis, bronchitis, accompanied by bipphasic fever. Feline calicivirus infection is a common disease in cats, with a high incidence and low mortality. Detecting FCV antibody levels in cats can reflect the body's immune status.
Feline herpesvirus type I (FHV-1) is the pathogen of feline infectious nasal-bronchitis and belongs to the Alpha-herpesvirus subfamily of Herpesaceae. General clinical manifestations: at the beginning of the disease, it mainly manifests as symptoms of upper respiratory-tract infection. The sick cat shows a depressed spirit, anorexia, an increased body temperature, cough, sneezing, tearing, and eyes and nose secretion. The secretion initially are serous and, with the aggravation of the disease, turn purulent. Some cats develop mouth ulcers, pneumonia and vaginitis, while others have skin ulcers. This disease seriously endanger young cats. If not treated in a timely manner, the mortality rate can reach over 50%. Detecting FHV-1 antibody in cats can reflect the body's immune status.
Clinical Significance:
1)For pre-immunization evaluation;
2)For antibody titer detection after immunization;
3)For early detection and diagnosis of cat fever, herpes simplex and calicivirus infection.
This product utilizes fluorescence immunochromatography to quantitatively detect FPV, FCV and FHV antibodies content in cat blood. The basic principle is as follows: T and C lines respectively marked on the nitrocellulose membrane. The binding pad is sprayed with fluorescent nanomaterial markers that can specifically recognize FPV, FCV and FHV antibody. The FPV, FCV and FHV antibody in the sample first combines with the nano material marker to form a complex. Then, through chromatography, the complex moves upward to binds to T-line. When the test strip is irradiated by excitation light, the nanomaterial emits a fluorescent signal, and the intensity of this signal is positively correlated with the concentration of FPV, FCV and FHV antibody in the sample.
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