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Symmetric Dimethylarginine Test Kit (SDMA)
Detection Purpose
Symmetric dimethylarginine (SDMA)is a by-product of kidney metabolism and can be utilized as a biomarker for renal function. The SDMA level in the blood can indicate the function status of the kidney. Compared with creatinine testing results, SDMA can detect kidney function diseases such as acute kidney injury (AKI) and chronic kidney disease (CKD) at an earlier stage.
Detection Principle
This product utilizes fluorescence immunochromatography to quantitatively detect the SDMA content in dog or cat serum/plasma. The basic principle is as follows: T and C lines are respectively marked on the nitrocellulose membrane.The T line is coated with SDMA antigen a. The binding pad is sprayed with another fluorescent nano-material-labeled antibody b. The SDMA in the sample first combines with the nano-material-labeled antibody b to form a complex. Then, through chromatography, the complex moves upward to binds to with SDMA on the T line, When the test strip is irradiated by excitation light, the nanomaterial emits a fluorescent signal, and the intensity of this signal is negatively correlated with the concentration of antigen in the sample.
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