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Canine/Feline CystatinC Test Kit (CysC)
Detection Purpose
Cystatin C is one of the cysteine protease inhibitor proteins. So far, CysC is an endogenous substance that basically meets the requirements of ideal endogenous GFR (Glomerular Filtration Rate) markers. It is a newly developed indicator with good sensitivity and high specificity for evaluating dog kidney function.
Detection Principle
This product utilizes fluorescence immunochromatography to quantitatively detect the CysC content in whole blood, serum or plasma. The basic principle: T and C lines are respectively marked on the nitrocellulose membrane. The T line is coated with an antibody a that specifically recognizes the CysC antigen. The binding pad is sprayed with another fluorescent nano-material-labeled antibody b that specifically recognizes CysC. The CysC in the sample first combines with the nano-material-labeled antibody b to form a complex. Then, through chromatography, the complex moves upward to binds to T line antibody a, forming a sandwich structure. When the test strip is irradiated by excitation light, the nanomaterial emits a fluorescent signal, and the intensity of this signal is positively correlated with the concentration of CysC in the sample.
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